منابع مشابه
High-dose midazolam infusion for refractory status epilepticus.
OBJECTIVE This study compares 2 treatment protocols allowing low vs high continuous IV midazolam (cIV-MDZ) doses. METHODS We compared adults with refractory status epilepticus treated with a protocol allowing for high-dose cIV-MDZ (n = 100; 2002-2011) with those treated with the previous lower-dose cIV-MDZ (n = 29; 1996-2000). We collected data on baseline characteristics, cIV-MDZ doses, seiz...
متن کاملThe Efficacy of Propofol and Midazolam in Treatment of Refractory Status Epilepticus in Children
Background: In this study, we compared the efficacy and safety of propofol and midazolam in treatment of children’s refractory status epilepticus. Methods: We recruited 32 patients with refractory status epilepticus. Of those, 16 were treated primarily with midazolam and 16 received propofol. Results: We achieved complete seizure control in 6 (38%) patients treated by midazolam, and in 10 (63%)...
متن کاملStatus epilepticus and refractory status epilepticus management.
Status epilepticus (SE) describes persistent or recurring seizures without a return to baseline mental status and is a common neurologic emergency. SE can occur in the context of epilepsy or may be symptomatic of a wide range of underlying etiologies. The clinician's aim is to rapidly institute care that simultaneously stabilizes the patient medically, identifies and manages any precipitant con...
متن کاملRecurrent Metabolic Acidosis during High-dose Midazolam Therapy for Refractory Status Epilepticus
High-dose continuous midazolam therapy has been used successfully for control of refractory status epilepticus. However, normal anion gap (AG) metabolic acidosis, a deleterious complication of this therapy is underrecognized. Even though previously reported in an isolated case report in a pediatric patient, we observed similar complication in an adult patient. Stereotyped normal AG metabolic ac...
متن کاملAn Emergency Medicine Perspective for Non-Convulsive Status Epilepticus Patients: Intravenous Midazolam
Non-convulsive status epilepticus (NCSE) characterized primarily by changes in consciousness in association with typical electroencephalography (EEG) changes is not very common; however, it is usually difficult to diagnose this SE type. NCSE should be one of the differential diagnoses for patients who present to the emergency department with impaired consciousness. There is no standard approach...
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ژورنال
عنوان ژورنال: Australian Prescriber
سال: 2017
ISSN: 1839-3942
DOI: 10.18773/austprescr.2017.005